Cryptotanshinone是什么

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August undefined, 2024

WebCryptotanshinone (CPT) is a natural compound extracted from herbal medicine that has been previously shown to possess antitumor properties in various types of human cancer cells. In the present study, we examined the potential role of CPT in the treatment of colorectal cancer. Using SW480, HCT116, a … WebNational Center for Biotechnology Information

Cryptotanshinone (Cryptotanshinon) Autophagy …

WebAug 13, 2024 · Hepatocellular carcinoma (HCC) is a fatal and dominant form of liver cancer that currently has no effective treatment or positive prognosis. In this study, we explored the antitumor effects of cryptotanshinone (CPT) against HCC and the molecular mechanisms underlying these effects using a systems pharmacology and experimental validation … WebTanshinone IIA, cryptotanshinone and tanshinone I are the main antitumor ingredients of Salvia miltiorrhiza. The antitumor mechanisms of tanshinone IIA are as follows: (1) … simple booking voucher code

Cryptotanshinone prevents muscle wasting in CT26-induced …

WebNational Center for Biotechnology Information WebMar 10, 2024 · Cryptotanshinone (CTS) is a lipophilic constituent of Salvia miltiorrhiza, with a broad-spectrum anticancer activity. We have observed that CTS enhances the efficacy of gefitinib in human lung cancer H1975 cells, yet little is known about its molecular mechanism. To explore how CTS enhances H1975 cell sensitivity to gefitinib, we figured … WebCryptotanshinone is a quinoid diterpene isolated from the root of the Asian medicinal plant, Salvia miotiorrhiza bunge. Recently it was discovered that the compound is a potent STAT3 inhibitor. Cryptotanshinone rapidly inhibited STAT3 Tyr705 phosphorylation through a JAK2-independent mechanism. Cryptotanshinone selectively inhibits STAT3 ... simple book it

Cryptotanshinone 隐丹参酮_STAT_JAK/STAT_抑制剂＆拮

Cryptotanshinone Attenuates Oxidative Stress and Inflammation ... - PubMed

WebDec 30, 2024 · Cryptotanshinone (CT), a diterpene that is isolated from Salvia miltiorrhiza Bunge, exhibits anti-cancer, anti-oxidative, anti-fibrosis, and anti-inflammatory properties. Here, we examined whether CT administration possess a hepatoprotective effect on chronic ethanol-induced liver injury. We established a chronic alcohol feeding mouse model ... WebTanshinone. Tanshinones are a class of chemical compounds. Examples include dihydrotanshinone, tanshinone I, or tanshinone IIA. These compounds are all naturally … ravin inspectionWebIn this review, we intend to summarize the anti-cancer properties of Cryptotanshinone (CPT), an extract of Danshen (the root of Salvia miltiorrhiza Bunge), on different types of cancer. Cancer is among the most life-threatening diseases worldwide. Along with conventional therapies like chemotherapy, surgery, and radiotherapy, alternative ... ravin lighted arrows turn off

"WebAug 23, 2024 · Cryptotanshinone (Cry) has multiple potential functions in treating different diseases. Most studies on Cry focus on its pharmacological effects and mechanisms, but toxicological reports on Cry are rare. Zebrafish is used as a model organism in drug development as it saves costs and time. This work aimed to investigate the toxicity of Cry … " - Cryptotanshinone是什么

Cryptotanshinone是什么

WebCryptotanshinone (CT), one major lipophilic component isolated from Salvia miltiorrhiza Bunge, has shown to possess chemopreventive properties against various types of … WebNov 11, 2008 · Abstract. Tanshinones are the major bioactive compounds of Salvia miltiorrhiza Bunge (Danshen) roots, which are used in many therapeutic remedies in Chinese traditional medicine. We investigated the anticancer effects of tanshinones on the highly invasive human lung adenocarcinoma cell line, CL1-5. Tanshinone I significantly inhibited …

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WebApr 18, 2024 · Cryptotanshinone (CTs), an active component isolated from the root of Salvia miltiorrhiza (SM), has been shown to exert potent neuroprotective property. We here established an oxygen-glucose deprivation/recovery (OGD/R)-injured Neurovascular Unit (NVU) model in vitro to observe the neuroprotective effects of CTs on cerebral … WebMar 19, 2024 · Cancer is a common malignant disease worldwide with an increasing mortality in recent years. Salvia miltiorrhiza, a well-known traditional Chinese medicine, has been used for the treatment of cardiovascular and cerebrovascular diseases for thousands of years. The liposoluble tanshinones in S. miltiorrhiza are important bioactive …

WebCryptotanshinone 是一种STAT3抑制剂，无细胞试验中IC50为4.6 μM，强烈抑制STAT3 Tyr705磷酸化，对STAT3 Ser727作用效果弱，对STAT1和STAT5没有作用效果 … Web2.4 Antitumor. Tanshinone IIA, cryptotanshinone and tanshinone I are the main antitumor ingredients of Salvia miltiorrhiza. The antitumor mechanisms of tanshinone IIA are as follows: (1) inhibiting the growth and proliferation of cancer cells, (2) inducing apoptosis, (3) inducing cell cycle arrest, and (4) inhibiting the invasion, migration and ...

WebCryptotanshinone 隐丹参酮. CAS: 35825-57-1. 分子式: C 19 H 20 O 3. 分子量: 296.37. 外观（性状）: Orange Solid. 储存条件: Powder : 2-8℃, 2 years; In solvent (母液): -20℃, 1 … WebMar 2, 2024 · Cryptotanshinone (CPT), as a major component of Salvia miltiorrhiza Bunge (Danshen), displays many pharmacological activities including anti-inflammatory effects. However, the exact cellular and molecular mechanisms of the anti-inflammatory activities of CPT remain to be elucidated. The present study was aimed to clarify its mechanisms on …

WebOct 5, 2024 · Results. In CT26 tumor-bearing mice, cryptotanshinone (20 and 60 mg/kg) administration drastically prevented systemic cancer cachexia from whole body weight loss and wasting of multiple tissues including heart, fat and skeletal muscle, with a negligible effect on cancer growth at dose of 20 mg/kg cryptotanshinone administration prevented … ravinia showsWebCryptotanshinone (CTS) is a natural compound involved in antioxidant and anti-inflammatory activities. We evaluated the effects of CTS on inflammation and oxidative stress in obstructed kidneys. Mice received gastric gavage of CTS from 7 days before unilateral ureteral obstruction operation to 1 week after surgery. Administration of CTS at … ravin lighted nock replacementWebMar 19, 2024 · The antitumor mechanism of CT. Cryptotanshinone inhibits the proliferation of cancer cells and induces autophagy and apoptosis by inhibiting IGF-1, IL-6, and … simple bookkeeping contract templateWebJul 1, 2024 · Abstract. Cryptotanshinone is a diterpene quinone derived from the roots of Salvia miltiorrhiza Bunge. An increasing number of studies have demonstrated that cryptotanshinone has the pharmacological activities such as anti-oxidative stress, anti-bacteria, anti-inflammation, and anti-cancer. Cryptotanshinone has been found to … ravin in hindiWebCryptotanshinone is a quinoid diterpene isolated from the root of the Asian medicinal plant, Salvia miotiorrhiza bunge. Recently it was discovered that the compound is a potent … ravin lighted nocks reviewWebAug 13, 2024 · Results: The combination of fosfomycin and cryptotanshinone had a synergistic effect on most (71.43%) of the FRSA and had a partial (28.57%) synergistic effect on a small part. In addition, time sterilization curve verified synergistic activity between cryptanshinone and fosfomycin against FSSA and FRSA, especially when fosfomycin was … ravinia seating mapWebSep 16, 2016 · Cryptotanshinone reverses the ovarian IR and significantly increases 2-deoxy-D-[1,2-3 H]-glucose uptake in all examined tissues from the DEX-treated mice.Cryptotanshinone significantly reduces the … ravin lighted nock tool